Genetics of Development and Aging

Genetics of Development and Aging

Traditionally, development and behavior have been viewed as separate fields. It is becoming increasingly evident, however, that development and behavior rely on common sets of genes and molecules. Additionally, normal functioning of organ systems that serve behavior is directly tied to appropriate development of these systems. Thus, the biology of development and behavior are intimately bound, and gaining an understanding in one area can greatly facilitate advances in the other.

Faculty members working in this area constitute an especially diverse group. Graduate students can train in laboratories employing the most powerful of genetic model systems in animals (mouse, Drosophila, and zebra fish), plants (Arabidopsis) or microbes toward investigating the molecular underpinnings of establishing a body plan, differentiation and specialization of cells, or behavioral responses to external stimuli. Students also have the opportunity to train in systems that have obvious connections to improving agricultural production. Additionally, students can explore the relationship between mutations and disease in humans or animals. Regardless of the research mentor, students in this area gain broad training in classical genetics, molecular genetics, and molecular biology, with specialized training in fields ranging from learning and memory, genomic analyses, anatomy, breeding, linkage analyses and regulation of gene 

David Arnosti
David Arnosti

Regulation of transcription via transcriptional repressors during development of the fruit fly Drosophila

Ingo Braasch
Ingo Braasch

(Intergrative Biology), Comparative genomics and gene family evolution in vertebrates, Evo-Devo, developmental genetics in zebrafish and other fish systems. braasch@msu.edu

Chen Chen
Chen Chen

Genetics of germ cell development

Henry Chung
Henry Chung

(Entomology) Investigating the molecular mechanisms underlying environmental adaptation and reproductive isolation. hwchung@msu.edu

Yuehua Cui
Yuehua Cui

Functional mapping longitudinal/dynamic gene effect

Ke Dong
Ke Dong

Molecular genetics, electrophysiology, and pharmacologyof insect voltage-gated sodium and calcium channels; molecular mechanisms of insecticide resistance.

Catherine Ernst
Catherine Ernst

Transcriptional regulation and QTL discovery in pigs; genetics of skeletal muscle development and behavior.

David R. Foran
David R. Foran

Development and gene expression of forensically useful flies 

Julia Ganz
Julia Ganz

(Integrative Biology) Development and regeneration of the enteric nervous system (ENS) in zebrafish; Zebrafish CRISPR gene knock-out models for ENS diseases; Signaling pathways in neural crest development. ganz@msu.edu

Jianping Hu
Jianping Hu

Genetic analysis of peroxisome functions in embryogenesis, photomorphogenesis, and other developmental pathways

Lee Kroos
Lee Kroos

Regulation of gene expression during cellular differentiation of the soil bacterium Bacillus subtilis

Keith Latham
Keith Latham

Molecular, cellular, genetic and epigenetic redulation of mammalian oocyte biology and preimplantation embryo development.

Beronda Montgomery
Beronda Montgomery

Genetic basis for photomorphogenesis in plants and cyanobacteria

Amy Ralston
Amy Ralston

Mammalian stem cells and development

Gemma Reguera
Gemma Reguera

Molecular genetics of microbial energy transduction: genetics and enviornmental engineering; applied microbiology for bioremediation, nanobiotechnology and bioenergy

Brian C. Schutte
Brian C. Schutte

Genetic and molecular genetic approaches to study craniofacial development in humans and in murine models.

Jose Teixeira
Jose Teixeira

Use mouse models in vivo and human cells in vitro to study the molecular mechanisms of reproductive tract and gonadal development and the pathological consequences of their dysregulation.

Frances Trail
Frances Trail

Genetic and genomic analysis of gene expression and development of the mycotoxigenic fungus Gibberella zeae

Steve Van Nocker
Steve Van Nocker

Molecular basis for flowering and fruiting in the model plant Arabidopsis thaliana

Jeremy Van Raamsdonk
Jeremy Van Raamsdonk

The relationship between reactive oxygen species and aging; aging and the mitochondria