Genomics and Proteomics

Genomics and Proteomics

Genomics and proteomics are just two of the terms used to describe the identification and characterization of set of genes, RNA, and proteins that comprise an organism. As exemplified by the Human Genome Project, the development of molecular maps, DNA chips and other high-throughput research tools have produced great advances and new insights for biology. With the help of these tools, it is now possible to understand how genotype leads to phenotype, how an organism responds to the environment, and other complex biological questions.

MSU scientists are leading a number of efforts for the development and the implementation of genomic tools in human, plant, animal and microbial species. Although the organisms under study are diverse, the application of common approaches forms natural ties that unify the research groups and promotes comparative genomics.

Hsu, Polly
Hsu, Polly

(Department of Biochemistry & Molecular Biology)

Using experimental and computational approaches to study genome-wide mRNA translation and identify novel peptides; plant responses under diurnal cycles and environmental stress; circadian rhythms.

pollyhsu@msu.edu

Andrea Amalfitano
Andrea Amalfitano

Utilizing array based technologies to evaluate the impact that various gene transfer modalities have upon mammalian cells and/or living animals

Ingo Braasch
Ingo Braasch

(Intergrative Biology), Comparative genomics and gene family evolution in vertebrates, Evo-Devo, developmental genetics in zebrafish and other fish systems. braasch@msu.edu

Christoph Benning
Christoph Benning

Biosynthesis, turnover, trafficking and function of lipids in photosynthetic organisms; genetics, genomics and engineering of algae and plants.

Christina Chan
Christina Chan

Apply system biology approaches to reconstruct signaling and gene regulatory pathways to help elucidate disease mechanisms and identify pharmaceutical targets

Chen Chen
Chen Chen

Small RNAs and germ cell proteomics

Hans Cheng
Hans Cheng

Structural and functional genomics of disease resistance in chicken

Paul Coussens
Paul Coussens

Genetics of immune responses to chronic infections caused by Mycobacteria and some retroviruses.

Dean DellaPenna
Dean DellaPenna

Functional genomics of plants to accomplish nutritional improvement

Yann Dufour
Yann Dufour

Genetic basis of phenotypic diversity in bacterial social behavior, cell-to-cell signaling, and chemotaxis.

Catherine Ernst
Catherine Ernst

Transcriptional regulation and QTL discovery in pigs; genetics of skeletal muscle development and behavior.

Eva Maria Farre
Eva Maria Farre

Genomics and proteomics of plant circadiian networks

Monique Floer
Monique Floer

Chromatin architecture and gene regulation; proinflammatory genes of mouse macrophages

Maren Friesen
Maren Friesen

Ecological genomics.

Jason Gallant
Jason Gallant

The Gallant lab is interested in understanding the genomic basis for the orgin and diversification of electrogenesis in teleost fishes.

Kyung-Hwan Han
Kyung-Hwan Han

Molecular biology of secondary growth (i.e., wood formation) Transcriptional regulation of secondary wall biosynthesis Molecular biology of drought tolerance

Susanne Hoffmann-Benning
Susanne Hoffmann-Benning

The role of lipids and small molecules in intracellular and long-distance signaling in plant development and the response to environmental changes.

Gregg Howe
Gregg Howe

Hormone signaling for control of plant growth, defense, and energy partitioning

Jianping Hu
Jianping Hu

Molecular regulation of the dynamics of plant energy organelles peroxisomes and mitochondria

Wen Huang
Wen Huang

(Animal Science), Genetics and evolution of complex quantitative traits using a combination of computational and empirical approaches. huangw53@msu.edu